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Concomitant cerebral aspergillosis and mucormycosis in an immunocompetent woman treated with corticosteroids.
Journal of Neurovirology ( IF 2.3 ) Pub Date : 2019-11-11 , DOI: 10.1007/s13365-019-00804-4
Vittorio Mantero 1 , Paola Basilico 1 , Ugo Pozzetti 2 , Silvia Tonolo 3 , Giorgio Rossi 4 , Giannantonio Spena 5 , Andrea Rigamonti 1 , Andrea Salmaggi 1
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We present the case of an immunocompetent 55-year-old woman, treated with corticosteroids, developing a cerebral fungal infection with autoptic ascertainment of aspergillosis and mucormycosis. This is the first report of cerebral co-infection by mucorales and aspergillus in an immunocompetent host. A possible explanation is that corticosteroids, even if taken for a short time, led to a transient lowering of immune function and contributed to negative outcome.

中文翻译:

一名接受皮质类固醇激素治疗的免疫功能正常的妇女伴有脑曲霉病和毛霉菌病。

我们介绍了一名具有免疫能力的55岁女性的案例,该患者接受皮质类固醇激素治疗,发展为脑真菌感染,并有自发性确定曲霉菌病和毛霉菌病。这是有免疫能力的宿主中粘膜炎和曲霉菌引起的脑部共同感染的首次报道。可能的解释是,即使短暂服用皮质类固醇,也会导致免疫功能暂时降低,并导致阴性结果。
更新日期:2019-11-11
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