This article is based on my presentation at the 9th International Congress of the Growth Hormone Research and Insulin-like Growth Factor (IGF) Societies at Seattle, USA on 17th, September 2018. In the article, after a general introduction to IGF research, I briefly review the IGF research being published from 2016 to 2018, focusing on what I believe represent the most interesting areas of progress. These areas include ligands of the IGF-I receptor, ligand binding to the IGF-I receptor, long-term signaling through the IGF-I receptor, intracellular organelles where IGF signals are transmitted, and novel functions of the IGFBPs. Lastly, I discuss future directions of IGF research from my point of view.

本文基于我在2018年9月17日在美国西雅图举行的第9届国际生长激素研究和胰岛素样生长因子（IGF）学会国际大会上的演讲。在对IGF研究进行一般介绍之后，我简要回顾一下2016年至2018年发布的IGF研究，重点是我认为代表了最有趣的进展领域。这些区域包括IGF-1受体的配体，与IGF-1受体的配体结合，通过IGF-1受体的长期信号传导，IGF信号在其中传递的细胞内细胞器以及IGFBP的新功能。最后，我从我的角度讨论了IGF研究的未来方向。