Kingella kingae colonizes the upper airways in children and has been recognized as the most common causative agent of osteoarticular infections (OAI) in children below 4 years of age. This is the first Scandinavian study to investigate oropharyngeal K. kingae carriage in healthy children. From June 2015 to August 2016, we recruited 198 healthy children aged 11-14 months from routine consultations at health promotion centers in Hordaland County, Norway for a cross-sectional study. After their parents had provided informed consent; demographic data were registered, and an oropharyngeal swab was collected. The oropharyngeal swab was analyzed with a real-time PCR assay specific to K. kingae targeting the RTX toxin locus. Results showed an asymptomatic carriage rate of 12.6%. A striking and highly significant difference was observed between the children that had started attending day care facilities as compared with children still being at home (33.33% vs 8.5%; p < 0.001). K. kingae is prevalent in young children in Norway. This study emphasize that K. kingae should be considered an important etiological agent in OAI. Transmission seems to be facilitated in day care facilities. The correlation between oropharyngeal carriage and OAI needs to be further explored.

中文翻译：

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关于斯堪的纳维亚儿童口咽部金氏菌金车的流行病学的第一份报告：在挪威西部的日托设施中，金刚氏菌的车很常见。

Kingella kingae定植在儿童的上呼吸道中，并已被公认为4岁以下儿童中最常见的骨关节炎感染（OAI）病因。这是斯堪的纳维亚的第一项研究健康儿童口咽K. kingae运输的研究。从2015年6月到2016年8月，我们从挪威霍达兰县健康促进中心的例行咨询中招募了198名年龄在11-14个月之间的健康儿童，以进行横断面研究。在父母提供知情同意后；记录人口统计数据，并收集口咽拭子。用针对RTX毒素基因座的金黄色K.菌特有的实时PCR分析法分析口咽拭子。结果显示无症状携带率为12.6％。与仍在家中的孩子相比，在开始使用日托设施的孩子之间观察到了惊人的，非常显着的差异（33.33％比8.5％； p <0.001）。金黄色K.菌在挪威的幼儿中很普遍。这项研究强调，K。kingae应该被认为是OAI的重要病原体。日间护理设施似乎促进了传播。口咽运输与OAI之间的相关性有待进一步探讨。