The development and persistence of memory T cells are integral to effective host defenses. Cell metabolism has a central role in the maintenance of these populations and engagement of specific metabolic pathways can influence T-cell fate. Nuances in memory T-cell metabolism are both context dependent, and exist, on a spectrum that complements and supports the activity of specific memory T-cell subsets. This review explores how metabolic pathways and substrate choice can influence the phenotype and function of memory T cells.

中文翻译：

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记忆T细胞的代谢谱。

记忆T细胞的发育和持久性是有效宿主防御必不可少的部分。细胞代谢在维持这些人群中起着核心作用，特定代谢途径的参与会影响T细胞的命运。记忆T细胞代谢的细微差别既取决于上下文，也存在于补充和支持特定记忆T细胞亚群活动的频谱上。这篇综述探讨了代谢途径和底物选择如何影响记忆T细胞的表型和功能。