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The microbiome and immune memory formation.
Immunology and Cell Biology ( IF 3.2 ) Pub Date : 2019-06-05 , DOI: 10.1111/imcb.12273
Kathy D McCoy 1 , Regula Burkhard 2 , Markus B Geuking 2
Affiliation  

The microbiota plays an important role in regulating both the innate and adaptive immune systems. Many studies have focused on the ability of microbes to shape the immune system by stimulating B-cell and antibody responses and the differentiation of T helper cell function. However, an important feature of the immune system is its ability to generate memory responses, which provide increased survival for the host. This review will highlight the role of the microbiota in the induction of immune memory with a focus on both adaptive and innate memory as well as vaccine efficacy.

中文翻译:

微生物组和免疫记忆的形成。

微生物群在调节先天和适应性免疫系统中都起着重要作用。许多研究集中于微生物通过刺激B细胞和抗体反应以及T辅助细胞功能的分化来塑造免疫系统的能力。然而,免疫系统的一个重要特征是它能够产生记忆反应,从而为宿主提供更长的生存期。本文将重点介绍微生物群在诱导免疫记忆中的作用,重点是适应性记忆和先天记忆以及疫苗功效。
更新日期:2019-11-01
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