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Neurobehavioral toxicity of methylmercury and PCBs Effects-profiles and sensitive populations.
Environmental Toxicology and Pharmacology ( IF 4.3 ) Pub Date : 2002-09-01 , DOI: 10.1016/s1382-6689(02)00030-3
M Christopher Newland 1
Affiliation  

A large and growing body of literature is available on the neurotoxicity of methylmercury and PCBs as expressed in the behavior of both humans and laboratory animals. Methylmercury and PCBs will be compared with PCBs with attention directed at overlaps and distinctions in their profiles of neurotoxicity. It is possible with methylmercury and, to a lesser extent, with PCBs to characterize the sensory, motor, and cognitive consequences of exposure. Methylmercury is emerging as a life-span developmental neurotoxicant: adverse effects of exposure have been identified in development and during aging in human populations as well as in laboratory animals. Less is known about the PCBs on this count. While the mechanisms of neurotoxicity are not understood for either class of compounds, emerging clues are pointing to the possibility of overlap in some mechanisms of neurotoxicity.

中文翻译:

甲基汞和多氯联苯的神经行为毒性作用概况和敏感人群。

关于甲基汞和多氯联苯对人和实验动物行为的神经毒性的文献越来越多。甲基汞和多氯联苯将与多氯联苯进行比较,并要注意它们在神经毒性方面的重叠和区别。甲基汞有可能,在较小程度上,PCB可以表征暴露的感觉,运动和认知后果。甲基汞正在作为一种终生的发育性神经毒剂出现:在人类以及实验动物的发育和衰老过程中,已经确定了暴露的不利影响。对PCB的了解甚少。虽然对于任何一类化合物都不了解神经毒性的机制,
更新日期:2019-11-01
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