We will describe eight interesting reactions using naltrexone derivatives. Almost all these reactions are characteristic of naltrexone derivatives, and can lead to the synthesis of many novel skeletons that provide new interesting pharmacological data. Some of the new reactions that were found with naltrexone derivatives were expanded into general reactions. For example, the reaction of 6alpha-hydroxyaldehyde derived from naltrexone led to the oxazoline dimer and the 1,3,5-trioxazatriquinane skeleton (triplet drug); this reaction was applied to general ketones which were converted to alpha-hydroxyaldehydes, followed by conversion to dimers and trimers, as described in Sect. 7.

中文翻译：

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纳曲酮衍生的新型基本骨架的合成。

我们将描述使用纳曲酮衍生物的八个有趣的反应。几乎所有这些反应都是纳曲酮衍生物的特征，并且可以导致合成许多提供新的有趣药理学数据的新颖骨架。与纳曲酮衍生物一起发现的一些新反应扩展为一般反应。例如，衍生自纳曲酮的6α-羟醛反应生成恶唑啉二聚体和1,3,5-三氧杂氮杂三喹烷骨架（三联体药物）；将该反应应用于一般的酮，将其转化为α-羟醛，然后转化为二聚体和三聚体，如Sect。7。