Pseudomonas aeruginosa is generally described as ubiquitous in natural settings, such as soil and water. However, because anecdotal observations and published reports have questioned whether or not this description is true, we undertook a rigorous study using three methods to investigate the occurrence of P. aeruginosa: We investigated environmental samples, analyzed 16S rRNA data, and undertook a systematic review and meta-analysis of published data. The environmental sample screening identified P. aeruginosa as significantly associated with hydrocarbon and pesticide-contaminated environments and feces, as compared to uncontaminated environments in which its prevalence was relatively low. The 16S rRNA data analysis showed that P. aeruginosa sequences were present in all habitats but were most abundant in samples from human and animals. Similarly, the meta-analysis revealed that samples obtained from environments with intense human contact had a higher prevalence of P. aeruginosa compared to those with less human contact. Thus, we found a clear tendency of P. aeruginosa to be present in places closely linked with human activity. Although P. aeruginosa may be ubiquitous in nature, it is usually scarce in pristine environments. Thus, we suggest that P. aeruginosa should be described as a bacterium largely found in locations associated with human activity.

中文翻译：

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铜绿假单胞菌的环境发生。

铜绿假单胞菌通常被描述为在自然环境中普遍存在，例如土壤和水。但是，由于轶事观察和已发表的报告都质疑此描述是否正确，因此我们使用三种方法进行了严格的研究，以调查铜绿假单胞菌的发生：我们调查了环境样本，分析了16S rRNA数据，并进行了系统评价和已发布数据的荟萃分析。与未经污染的环境相比，铜绿假单胞菌与碳氢化合物和农药污染的环境和粪便具有显着相关性，而未经污染的环境中铜绿假单胞菌的患病率相对较低。16S rRNA数据分析表明，铜绿假单胞菌序列存在于所有生境中，但在人类和动物的样品中含量最高。同样，荟萃分析显示，与人类接触较少的环境相比，从与人类紧密接触的环境中获取的样品铜绿假单胞菌的患病率更高。因此，我们发现在与人类活动密切相关的地方存在铜绿假单胞菌的明显趋势。尽管铜绿假单胞菌在自然界可能无处不在，但在原始环境中通常很少。因此，我们建议将铜绿假单胞菌描述为一种主要在与人类活动相关的位置发现的细菌。在原始环境中通常很少。因此，我们建议铜绿假单胞菌应被描述为一种主要在与人类活动相关的位置发现的细菌。在原始环境中通常很少。因此，我们建议铜绿假单胞菌应被描述为一种主要在与人类活动相关的位置发现的细菌。