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Genetics of cardiac repolarization.
Nature Genetics ( IF 31.7 ) Pub Date : 2009-04-01 , DOI: 10.1038/ng0409-388 Svati H Shah 1 , Geoffrey S Pitt
Nature Genetics ( IF 31.7 ) Pub Date : 2009-04-01 , DOI: 10.1038/ng0409-388 Svati H Shah 1 , Geoffrey S Pitt
Affiliation
Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide association studies (GWAS) of variation in the QT interval in population-based cohorts now report association with variants in a subset of ion channel genes and other new associations.
中文翻译:
心脏复极的遗传学。
心电图 QT 间期延长是心脏复极的一种衡量标准,与心律失常相关,是心脏性猝死的危险因素。两项基于人群的队列中 QT 间期变异的全基因组关联研究 (GWAS) 现在报告与离子通道基因子集的变异和其他新关联的关联。
更新日期:2019-11-01
中文翻译:
心脏复极的遗传学。
心电图 QT 间期延长是心脏复极的一种衡量标准,与心律失常相关,是心脏性猝死的危险因素。两项基于人群的队列中 QT 间期变异的全基因组关联研究 (GWAS) 现在报告与离子通道基因子集的变异和其他新关联的关联。