The Douglas Mental Health University Institute, in collaboration with the McGill Centre for Studies in Aging, organized a 2-day symposium entitled “Biological Changes Associated with Healthy Versus Pathological Aging” that was held in 13 and 14 December 2007 on the Douglas campus. The symposium involved presentations on current trends in aging and dementia research across several sub-disciplines: genetics, neurochemistry, structural and functional neuroimaging and clinical treatment and rehabilitation. The goal of this symposium was to provide a forum for knowledge-transfer between scientists and clinicians with different specializations in order to promote cross-fertilization of research ideas that would lead to future collaborative neuroscience research in aging and dementia. In this review article, we summarize the presentations made by the 13 international scientists at the symposium and highlight: (i) past research, and future research trends in neuroscience of aging and dementia and (ii) links across levels of analysis that can lead to fruitful transdisciplinary research programs that will advance knowledge about the neurobiological changes associated with healthy aging and dementia.

道格拉斯心理健康大学研究所与麦吉尔衰老研究中心合作，于 2007 年 12 月 13 日至 14 日在道格拉斯校区举办了为期两天的研讨会，主题为“与健康与病理衰老相关的生物变化”。研讨会涉及多个子学科的衰老和痴呆研究的当前趋势：遗传学、神经化学、结构和功能神经影像学以及临床治疗和康复。本次研讨会的目标是为不同专业的科学家和临床医生之间的知识转移提供一个论坛，以促进研究思想的交叉融合，从而导致未来衰老和痴呆症的神经科学研究合作。在这篇评论文章中，