Thermodynamical techniques are applied for determining the thermal stress of medicinal compounds of the excipients as well as their interactions during the formulation process. The physicochemical properties and the stability of the medicinal products could be measured as a function of temperature or time using thermal analysis. Differential Scanning Calorimetry (DSC) is a suitable thermal analysis technique for determining the purity, the polymorphic forms and the melting point of a sample in the Pharmaceutical Industry. It is also considered as a tool to study the thermal behavior of lipid bilayers and of lipidic drug delivery systems, like liposomes by measuring thermodynamic parameters (i.e. ΔH and Tm), which affect the stability of the liposomal suspension under given storage conditions.

中文翻译：

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差示扫描量热法 (DSC)：研究脂质双层热行为和脂质体稳定性的工具

热力学技术用于确定赋形剂的药用化合物的热应力以及它们在制剂过程中的相互作用。可以使用热分析作为温度或时间的函数来测量药品的理化特性和稳定性。差示扫描量热法 (DSC) 是一种合适的热分析技术，用于确定制药工业中样品的纯度、多晶型和熔点。它也被认为是通过测量影响脂质体悬浮液在给定储存条件下的稳定性的热力学参数（即 ΔH 和 Tm）来研究脂质双层和脂质药物递送系统（如脂质体）的热行为的工具。