Most of the current knowledge of the complex microbiology of oral biofilms, which initiates and maintains periodontal lesions, has been facilitated by the introduction of molecular techniques. Several studies exalt the high sensitivity and specificity of molecular tests in the detection and quantification of periodontal pathogens. Although they have large a diffusion, the old method of bacterial culture remains nowadays the gold standard when determining the utility of a new microbial test. Moreover, cultures have the important advantage of allowing an antibiotic sensitivity test and this is much more important during the treatment of patients with aggressive periodontitis.

中文翻译：

---

牙周病的诊断：通过微生物学检测可提供进一步的帮助。

分子技术的引入促进了对口腔生物膜的复杂微生物学的当前了解，而这种生物学知识可引发和维持牙周病变。数项研究提高了分子检测在牙周病原体检测和定量中的高灵敏度和特异性。尽管它们具有很大的扩散性，但是当确定一种新的微生物检测方法的实用性时，旧的细菌培养方法如今仍是当今的金标准。此外，培养物具有允许进行抗生素敏感性测试的重要优势，这在侵略性牙周炎患者的治疗期间更为重要。