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Candida species adhesion to oral epithelium: factors involved and experimental methodology used.
Critical Reviews in Microbiology ( IF 6.0 ) Pub Date : 2006-11-25 , DOI: 10.1080/10408410601023524
Mariana Henriques 1 , Joana Azeredo , Rosário Oliveira
Affiliation  

Due to the increasing prevalence and emergence of Non-Candida albicans Candida (NCAC) species, especially in immunosupressed patients, it is becoming urgent to deepen the current knowledge about virulence factors of these species. Adhesion of cells to epithelium is considered one of the major virulence factors of Candida species. However, relatively little is known concerning the adhesion mechanisms of NCAC species to epithelium, as well as about the factors affecting the adhesion process. This review focuses both the mechanisms that regulate the adhesion interactions and the factors involved and the description of the experimental methodology that has been used to perform the adhesion assays.

中文翻译:

念珠菌种对口腔上皮的粘附性:涉及的因素和使用的实验方法。

由于非白色念珠菌念珠菌(NCAC)种类的流行和出现,特别是在免疫抑制的患者中,加深对这些种类的毒力因子的当前认识变得迫在眉睫。细胞对上皮的粘附被认为是念珠菌物种的主要毒力因子之一。然而,关于NCAC物质对上皮的粘附机制以及影响粘附过程的因素的了解相对较少。这篇综述着重于调节粘附相互作用的机制和所涉及的因素,以及用于进行粘附测定的实验方法的描述。
更新日期:2019-11-01
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