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Experience with docetaxel in the treatment of gastric cancer.
Seminars in Oncology ( IF 4 ) Pub Date : 2005-07-15 , DOI: 10.1053/j.seminoncol.2005.04.004
Philip A Philip 1
Affiliation  

Gastric cancer is the second most common cause of cancer death worldwide. In operable patients, standard care includes surgery with or without adjuvant chemotherapy and radiotherapy; standard care for inoperable disease includes chemotherapy with or without radiotherapy. Docetaxel has shown in vitro and in vivo antitumor effects on human gastric cell lines and gastric cancer xenografts. Phase I through III trials of docetaxel alone and in combination with other chemotherapy agents have subsequently been conducted. This review provides an overview of these studies and suggestions for future directions in the treatment of gastric cancer.

中文翻译:

多西他赛治疗胃癌的经验。

胃癌是全球第二大最常见的癌症死亡原因。对于可手术患者,标准护理包括有或没有辅助化疗和放疗的手术;无法手术疾病的标准护理包括有或没有放疗的化学疗法。多西紫杉醇已显示出对人胃细胞系和胃癌异种移植物的体外和体内抗肿瘤作用。随后已进行了多西他赛单独或与其他化疗药物联合使用的I至III期试验。这篇综述概述了这些研究,并为治疗胃癌的未来方向提供了建议。
更新日期:2019-11-01
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