To determine the longitudinal association of baseline body mass index and change in body mass index over 8 years to incident of patellofemoral osteoarthritis at the 8-year follow-up. A sample of 528 women and men, aged 45-65 years, with knee complaints and without radiographic evidence of patellofemoral and tibiofemoral osteoarthritis at baseline, were selected from the Cohort Hip and Cohort Knee cohort. Incidence of patellofemoral osteoarthritis was defined as presence of radiographic patellofemoral osteoarthritis (with or without tibiofemoral osteoarthritis) at the 8-year follow-up. Baseline body mass index data were categorized into normal, overweight, and obese weight-categories. Logistic regression analyses, adjusted for age and sex, were conducted to determine the association of baseline body mass index and change in body mass index to patellofemoral osteoarthritis incidence 8 years later. Obesity was associated with greater odds of radiographic patellofemoral osteoarthritis incident (odds ratio: 1.8 [95% CI 1.1, 3.1]) 8 years later. There were no significant associations observed between body mass index change over 8 years and incidence of radiographic patellofemoral osteoarthritis in overweight and obese individuals. Obesity is associated with increased odds of developing radiographic patellofemoral osteoarthritis 8 years later.

中文翻译：

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肥胖与pa股骨关节炎的发生有关：队列髋关节和队列膝关节（CHECK）研究。

为了确定基线体重指数的纵向关联以及在8年随访中8年内体重指数在change股股骨关节炎事件中的变化。从队列髋关节和队列膝关节队列中选择了528名年龄在45-65岁之间，有膝关节不适且在放射学上没有radio股和胫股骨骨关节炎的影像学证据的男女。of股骨关节炎的发生率定义为在8年的随访中是否存在影像学上的pa股骨关节炎（伴或不伴胫股骨骨关节炎）。基线体重指数数据分为正常，超重和肥胖体重类别。逻辑回归分析，根据年龄和性别进行调整，进行了确定基线体重指数和体重指数变化与8股骨关节炎发生率之间的关系的研究，时间为8年。肥胖与8年后放射影像pa股骨关节炎事件的几率更高有关（赔率：1.8 [95％CI 1.1，3.1]）。在超重和肥胖个体中，超过8年的体重指数变化与X线股pa股骨关节炎的发生率之间没有显着相关性。肥胖与8年后发生放射影像pa股骨关节炎的几率增加有关。在超重和肥胖个体中，超过8年的体重指数变化与X线股pa股骨关节炎的发生率之间没有显着相关性。肥胖与8年后发生放射影像pa股骨关节炎的几率增加有关。在超重和肥胖个体中，超过8年的体重指数变化与X线股pa股骨关节炎的发生率之间没有显着相关性。肥胖与8年后发生放射影像pa股骨关节炎的几率增加有关。