Children with homozygous familial hypercholesterolemia are at risk for early cardiovascular events secondary to coronary artery disease. Current medical therapy does not ameliorate this risk. Liver transplantation offers the most effective option to reduce circulating levels of low-density lipoprotein cholesterol and thereby reduce risk of cardiovascular events. Angiographic evidence of regression of coronary artery disease is presented.

中文翻译：

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纯合子家族性高胆固醇血症患儿的冠状动脉疾病：肝移植后的回归。

纯合子家族性高胆固醇血症的儿童有发生冠心病继发的早期心血管事件的风险。当前的药物治疗不能改善这种风险。肝移植提供了降低低密度脂蛋白胆固醇循环水平的最有效选择，从而降低了发生心血管事件的风险。提出了冠状动脉疾病消退的血管造影证据。