Cognitive deficits associated with early Alzheimer's disease (AD) have been recently operationalised in terms of an acquisition deficit and the research supporting this view is presented. However, there is still debate concerning the nature of this deficit and how underlying cognitive processes may be detrimentally affecting the ability to acquire new information in early AD. This review argues that the pattern of cognitive deficits contributing to the acquisition impairment in early AD patients may be readily interpreted within the context of a working memory model. Isolating the component processes of working memory that underlie the acquisition deficit in early AD patients will aid in the design of clinical applications that are focussed at enhancing the ability to acquire new information in everyday life.

中文翻译：

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早期阿尔茨海默氏病的工作记忆和学习。

与早期阿尔茨海默氏病（AD）相关的认知缺陷最近已在购置缺陷方面得到应用，并提出了支持该观点的研究。但是，关于这种缺陷的性质以及潜在的认知过程如何可能有害地影响AD早期获取新信息的能力，仍存在争议。这篇评论认为，在早期AD患者中导致认知障碍的模式可能很容易在工作记忆模型的背景下得到解释。隔离导致早期AD患者获取不足的工作记忆的组成过程，将有助于临床应用程序的设计，这些应用程序的重点是增强日常生活中获取新信息的能力。