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Chemical compositions and antimicrobial activities of four different Anatolian propolis samples.
Microbiological Research ( IF 6.1 ) Pub Date : 2005-05-11 , DOI: 10.1016/j.micres.2005.01.002
Ataç Uzel 1 , Kadriye Sorkun , Ozant Onçağ , Dilşah Cogŭlu , Omür Gençay , Bekir Salih
Affiliation  

Propolis means a gum that is gathered by bees from various plants. It is known for its biological properties, having antibacterial, antifungal and healing properties. The aims of this study were to evaluate the antimicrobial activity of four different Anatolian propolis samples on different groups of microorganisms including some oral pathogens and comparison between their chemical compositions. Ethanol extracts of propolis (EEP) were prepared from four different Anatolian propolis samples and examined whether EEP inhibit the growth of the test microorganisms or not. For the antimicrobial activity assays, minimum inhibitory concentrations (MIC) were determined by using macrodilution method. The MIC values of the most effective propolis (TB) were 2 microg/ml for Streptococcus sobrinus and Enterococcus faecalis, 4 microg/ml for Micrococcus luteus, Candida albicans and C. krusei, 8 microg/ml for Streptococcus mutans, Staphylococcus aureus, Staphylococcus epidermidis and Enterobacter aerogenes, 16 microg/ml for Escherichia coli and C. tropicalis and 32 microg/ml for Salmonella typhimurium and Pseudomonas aeruginosa. The chemical compositions of EEP's were determined by high-temperature high-resolution gas chromatography coupled to mass spectrometry. The main compounds of four Anatolian propolis samples were flavonoids such as pinocembrin, pinostropin, isalpinin, pinobanksin, quercetin, naringenin, galangine and chrysin. Although propolis samples were collected from different regions of Anatolia all showed significant antimicrobial activity against the Gram positive bacteria and yeasts. Propolis can prevent dental caries since it demonstrated significant antimicrobial activity against the microorganisms such as Streptococcus mutans, Streptococcus sobrinus and C. albicans, which involves in oral diseases.

中文翻译:

四种不同的安那托利亚蜂胶样品的化学成分和抗菌活性。

蜂胶是指由各种植物的蜜蜂收集的树胶。众所周知,它具有抗菌,抗真菌和愈合的生物学特性。这项研究的目的是评估四种不同的安纳托利亚蜂胶样品对包括某些口腔病原体在内的不同微生物群的抗菌活性,并对其化学成分进行比较。从四种不同的安那托利亚蜂胶样品中制备蜂胶乙醇提取物(EEP),并检查EEP是否抑制测试微生物的生长。对于抗微生物活性测定,通过使用宏观稀释法确定最小抑菌浓度(MIC)。最有效的蜂胶(TB)的MIC值对于链球菌和粪肠球菌为2微克/毫升,对黄褐微球菌为4微克/毫升,白色念珠菌和克鲁斯杆菌,变形链球菌,金黄色葡萄球菌,表皮葡萄球菌和产气肠杆菌为8微克/毫升,大肠杆菌和热带念珠菌为16微克/毫升,鼠伤寒沙门氏菌和铜绿假单胞菌为32微克/毫升。EEP's的化学成分是通过与质谱联用的高温高分辨率气相色谱法测定的。四个安那托利亚蜂胶样品的主要化合物是类黄酮,如松皮精,吡托辛,伊沙品素,松树素,槲皮素,柚皮素,高良姜精和菊花精。尽管从安纳托利亚的不同地区收集到的蜂胶样品都显示出对革兰氏阳性细菌和酵母菌的显着抗菌活性。
更新日期:2019-11-01
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