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Cardiac arrhythmias during normal sleep and in obstructive sleep apnea syndrome.
Sleep Medicine Reviews ( IF 10.5 ) Pub Date : 2004-08-18 , DOI: 10.1016/s1087-0792(98)90053-3
A Adlakha 1 , J W Shepard
Affiliation  

Normal sleep is associated with a slowing in heart rate due to a relative shift from sympathetic to parasympathetic neural dominance. Bradyarrhythmias consisting of sinus bradycardia, sinus arrest and second degree (Mobitz type 1) heart block are not uncommon in young adults. With aging, bradyarrhythmias decrease in frequency while atrial arrhythmias and ventricular ectopy increases. Patients with obstructive sleep apnea (OSA) have been demonstrated to have bradyarrhythmias and increased ventricular ectopy in association with apneas when oxyhemoglobin desaturations become severe. Although retrospective studies have suggested that cardiovascular mortality may be increased in patients with OSA, this remains to be proven in prospective clinical studies. Sudden death during sleep secondary to apnea related brady or ventricular tachyarrhythmias may occur. However, this is likely to be a very rare event that remains to be documented in the literature.

中文翻译:

正常睡眠和阻塞性睡眠呼吸暂停综合征期间的心律不齐。

由于从交感神经到副交感神经的相对转移,正常睡眠与心率减慢有关。在年轻人中,由窦性心动过缓,窦性心律停止和二级(Mobitz 1型)心脏传导阻滞引起的心律失常并不少见。随着年龄的增长,缓慢性心律失常的频率降低,而房性心律失常和心室异位的频率增加。当氧合血红蛋白饱和度严重升高时,阻塞性睡眠呼吸暂停(OSA)患者已被证明患有缓慢性心律失常和心室异位症伴呼吸暂停。尽管回顾性研究表明OSA患者的心血管死亡率可能会增加,但这仍需前瞻性临床研究证实。呼吸暂停相关性布雷迪或室性心律失常继发于睡眠中的猝死可能会发生。但是,这很可能是非常罕见的事件,有待文献记载。
更新日期:2019-11-01
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