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Models of human sleep regulation.
Sleep Medicine Reviews ( IF 11.2 ) Pub Date : 2004-08-18 , DOI: 10.1016/s1087-0792(98)90052-1
D G Beersma 1
Affiliation  

Non-REM sleep deprivation and REM sleep deprivation both lead to specific rebounds, suggesting that these states fulfil physiological needs. In view of impaired performance after sleep deprivation, a recovery function of sleep seems likely. The timing of this recovery is restricted to a narrow time interval within the 24 hour day, i.e. the night. Generally, nocturnal sleep in humans is considered a consequence of the impact of the circadian pacemaker in the hypothalamus on sleep propensity. The interaction between the homeostatic recovery process and the circadian pacemaker has been modelled in the two-process model of sleep regulation. This model is used as a starting point in the present review. A series of refinements and several alternative models are discussed, both with respect to the quality of fit of theory and data, as well as with respect to the concepts behind the models.

中文翻译:

人体睡眠调节模型。

非快速眼动睡眠剥夺和快速眼动睡眠剥夺都导致特定的反弹,表明这些状态满足生理需要。考虑到剥夺睡眠后性能受损,睡眠恢复功能似乎很可能。恢复的时间限制在一天的24小时(即晚上)内的狭窄时间间隔内。通常,人类的夜间睡眠被认为是下丘脑中昼夜节律起搏器对睡眠倾向的影响的结果。稳态调节过程和昼夜节律起搏器之间的相互作用已在睡眠调节的两个过程模型中进行了建模。该模型被用作本综述的起点。就理论和数据的拟合质量而言,讨论了一系列改进和几种替代模型,
更新日期:2019-11-01
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