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The association between delirium and cognitive decline: a review of the empirical literature.
Neuropsychology Review ( IF 5.4 ) Pub Date : 2004-07-22 , DOI: 10.1023/b:nerv.0000028080.39602.17
James C Jackson 1 , Sharon M Gordon , Robert P Hart , Ramona O Hopkins , E Wesley Ely
Affiliation  

Delirium is a common neurobehavioral syndrome that occurs across health care settings which is associated with adverse outcomes, including death. There are limited data on long-term cognitive outcomes following delirium. This report reviews the literature regarding relationships between delirium and cognitive impairment. Psych Info and Medline searches and investigation of secondary references for all English language articles on delirium and subsequent cognitive impairment were carried out. Nine papers met inclusion criteria and documented cognitive impairment in patients following delirium. Four papers reported greater cognitive impairment among patients with delirium than matched controls. Four papers reported higher incidence of dementia in patients with a history of delirium. One study found 1 of 3 survivors of critical illness with delirium developed cognitive impairment. The evidence suggests a relationship between delirium and cognitive impairment, although significant questions remain regarding the nature of this association. Additional research on delirium-related effects on long-term cognitive outcome is needed.

中文翻译:

del妄与认知能力下降之间的关联:经验文献综述。

r妄是一种常见的神经行为综合症,发生在医疗机构中,与包括死亡在内的不良后果有关。ir妄后长期认知结果的数据有限。本报告回顾了有关del妄与认知障碍之间关系的文献。进行了Psych Info和Medline搜索以及所有有关all妄及随后认知障碍的英语文章的二级参考文献的调查。九篇论文符合入选标准,并记录了ir妄后患者的认知障碍。四篇论文报道del妄患者的认知障碍程度高于对照组。四篇论文报道有in妄史的患者痴呆症的发生率较高。一项研究发现,3妄危重症幸存者中有3名出现了认知障碍。证据表明ir妄与认知障碍之间存在联系,尽管有关这种联系的性质仍存在重大疑问。需要进一步研究del妄相关的长期认知结果。
更新日期:2019-11-01
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