Economic evaluations are increasingly common in blood safety and transfusion medicine. We sought to summarize and review economic evaluations of donated blood interventions conducted in the United States. By using computer database searches, we identified 19 studies that reported both cost and health benefit results, and relative to each other, we rated the quality of their design and reporting. We classified 6 of the studies as having high quality, 10 as having fair quality, and 3 as having poor quality. Several strengths and limitations in economic evaluations of blood safety and transfusion medicine interventions were identified. Four key improvements can increase the quality of literature in this discipline. We believe researchers should (1) provide more explicit detail on cost parameters in each study and the methods used to obtain them; (2) adopt a clear analysis perspective relevant to decision makers that captures all key costs and consequences, such as the societal perspective; (3) use a consistent approach to reporting sensitivity analyses; and (4) place greater reliance on graphical presentation of results including sensitivity analyses because a large amount of information can be conveyed in relatively simple figures, leaving space to discuss the impact of important analysis assumptions and applicability of the results to other settings.

中文翻译：

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血液安全和输血药物干预措施的经济分析：系统评价。

经济评估在血液安全和输血医学中越来越普遍。我们试图总结和回顾在美国进行的献血干预的经济评估。通过使用计算机数据库搜索，我们确定了19项报告，报告了成本和健康收益结果，并且相对于彼此，我们对设计和报告的质量进行了评估。我们将研究中的6项归类为高质量，将10项归类为中等质量，将3项归类为劣质。在血液安全性和输血医学干预措施的经济评估中，确定了一些优势和局限性。四个关键的改进可以提高该学科文献的质量。我们认为研究人员应（1）在每项研究中提供有关费用参数及其获取方法的更明确的细节；（2）采取与决策者相关的清晰分析视角，该视角涵盖所有关键成本和后果，例如社会视角；（3）使用一致的方法报告敏感性分析；（4）更加依赖包括敏感性分析在内的结果的图形表示，因为可以通过相对简单的图形传达大量信息，从而留出了空间来讨论重要分析假设的影响以及结果对其他设置的适用性。