It is widely recognized that patients with cancer are at an increased risk of developing acute kidney injury (AKI) while undergoing cancer therapies, but to date, only small single-center studies have investigated the incidence of and risk factors for AKIs. However, a recent large-scale, population-based study (J Natl Cancer Inst. Published online November 13, 2018. doi:10.1093/ jnci/djy167) reports that although approximately 1 in 10 patients with cancer who receive systemic therapy experience AKIs that result in hospitalization or require acute dialysis, AKIs also may occur in patients with a wider array of cancers than previously suspected. The 5-year cumulative incidence of AKI overall for all types of cancer combined was 7.8%.

中文翻译：

---

严重的肾损伤可能与癌症治疗有关

人们普遍认为，癌症患者在接受癌症治疗时发生急性肾损伤 (AKI) 的风险会增加，但迄今为止，只有小型单中心研究调查了 AKI 的发生率和危险因素。然而，最近的一项基于人群的大规模研究（J Natl Cancer Inst. 2018 年 11 月 13 日在线发布。doi:10.1093/jnci/djy167）报告说，虽然大约十分之一的接受全身治疗的癌症患者经历了 AKI导致住院或需要急性透析，AKI 也可能发生在比以前怀疑的范围更广的癌症患者中。所有类型癌症的 AKI 总体 5 年累积发生率为 7.8%。