The aim of this study was to assess the prevalence of periodontal disease and the effect of periodontal treatment in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA). Forty-four RA patients, thirty SpA patients and thirty-nine healthy volunteers were recruited to the study. Periodontal examination included the approximal plaque index (API), bleeding on probing (BoP), probing depth (PD) and number of teeth. Samples from the deepest periodontal pockets were taken for the detection of Porphyromonas gingivalis DNA with the use of the polymerase chain reaction. All subjects with periodontitis, who completed the study, received periodontal treatment consisting of scaling/root planing and oral hygiene instructions. Disease activity scores, clinical and laboratory parameters were assessed before and 4-6 weeks after periodontal treatment. No significant difference in the prevalence of periodontal disease and the presence of P. gingivalis DNA were found in RA and SpA patients compared to healthy controls. Significantly higher API (80% vs 63%; p = 0.01) and a lower number of teeth (20 vs 25, p = 0.001) were found in RA patients. BoP was significantly elevated in SpA patients (51% vs 33%, p = 0.02). Disease activity measured by the DAS28(CRP) was significantly reduced in RA patients after periodontal treatment (p = 0.002). Clinical and biochemical parameters were not improved in SpA patients. Nonsurgical periodontal treatment had an impact on the decrease in RA activity. Periodontal examination is necessary in patients with RA to detect and treat periodontitis at an early stage.

中文翻译：

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类风湿关节炎和脊椎关节炎患者的牙周疾病和牙周治疗对疾病活动的影响。

这项研究的目的是评估类风湿关节炎（RA）和脊椎关节炎（SpA）患者的牙周病患病率和牙周治疗的效果。该研究招募了44名RA患者，30名SpA患者和39名健康志愿者。牙周检查包括大约牙菌斑指数（API），探查出血（BoP），探查深度（PD）和牙齿数量。使用聚合酶链反应从最深的牙周袋中取出样品，以检测牙龈卟啉单胞菌DNA。完成研究的所有患有牙周炎的受试者均接受了包括刮治/根部整治和口腔卫生说明在内的牙周治疗。在牙周治疗之前和之后的4-6周评估疾病活动评分，临床和实验室参数。与健康对照组相比，RA和SpA患者的牙周疾病患病率和牙龈卟啉单胞菌DNA的存在无显着差异。在RA患者中，API显着较高（80％比63％； p = 0.01）和更少的牙齿数量（20 vs 25，p = 0.001）。SpA患者的BoP显着升高（51％vs 33％，p = 0.02）。牙周治疗后，RA患者通过DAS28（CRP）测得的疾病活性显着降低（p = 0.002）。SpA患者的临床和生化指标没有改善。非手术牙周治疗对RA活动的减少有影响。RA的患者必须进行牙周检查以早期发现和治疗牙周炎。与健康对照组相比，RA和SpA患者中发现了牙龈DNA。在RA患者中，API显着较高（80％比63％； p = 0.01）和更少的牙齿数量（20 vs 25，p = 0.001）。SpA患者的BoP显着升高（51％vs 33％，p = 0.02）。牙周治疗后，RA患者通过DAS28（CRP）测得的疾病活性显着降低（p = 0.002）。SpA患者的临床和生化指标没有改善。非手术牙周治疗对RA活动的减少有影响。RA的患者必须进行牙周检查以早期发现和治疗牙周炎。与健康对照组相比，RA和SpA患者中发现了牙龈DNA。在RA患者中，API显着较高（80％比63％； p = 0.01）和更少的牙齿数量（20 vs 25，p = 0.001）。SpA患者的BoP显着升高（51％vs 33％，p = 0.02）。牙周治疗后，RA患者通过DAS28（CRP）测得的疾病活性显着降低（p = 0.002）。SpA患者的临床和生化指标没有改善。非手术牙周治疗对RA活动的减少有影响。RA的患者必须进行牙周检查以早期发现和治疗牙周炎。SpA患者的BoP显着升高（51％vs 33％，p = 0.02）。牙周治疗后，RA患者通过DAS28（CRP）测得的疾病活性显着降低（p = 0.002）。SpA患者的临床和生化指标没有改善。非手术牙周治疗对RA活动的减少有影响。RA的患者必须进行牙周检查以早期发现和治疗牙周炎。SpA患者的BoP显着升高（51％vs 33％，p = 0.02）。牙周治疗后，RA患者通过DAS28（CRP）测得的疾病活性显着降低（p = 0.002）。SpA患者的临床和生化指标没有改善。非手术牙周治疗对RA活动的减少有影响。RA的患者必须进行牙周检查以早期发现和治疗牙周炎。