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Antihypertensive effects of Korean wild simulated ginseng (Sanyangsam) extracts in spontaneously hypertensive rats.
Food Science and Biotechnology ( IF 2.4 ) Pub Date : 2019-06-07 , DOI: 10.1007/s10068-019-00617-5
Jae-Nam Moon 1 , Jong-Kuk Kim 2 , Seul Lee 1 , Joong-Ho Kwon 1
Affiliation  

Ginseng possesses a wide spectrum of medicinal effects and has widely been used in traditional medicine for thousands of years. In this study, the antihypertensive effect of Korean wild simulated ginseng in spontaneously hypertensive rats was investigated. Three groups of hypertensive rats-a group without wild simulated ginseng treatment; another group treated with 100 mg of wild simulated ginseng extract/kg of body weight; and the other group treated with 200 mg of wild simulated ginseng extract/kg of body weight were tested over 8 weeks. The two wild simulated ginseng-treated groups showed significantly (p < 0.05) reduced systolic blood pressure at 4 and 6 weeks of wild simulated ginseng treatment. However, the wild simulated ginseng treatment did not adversely affect the food intake, serum electrolytes, osmolality, heart weight, heart rate, and the cross-section of the aorta as well as enzyme activities. The results suggested that Korean wild simulated ginseng is effectively used for reducing high systolic blood pressure in hypertensive patients without causing adverse health effects.

中文翻译:

韩国野生人参提取物对自发性高血压大鼠的降压作用。

人参具有广泛的医学功效,并已在传统医学中广泛使用了数千年。在这项研究中,研究了韩国野生人参对自发性高血压大鼠的降压作用。三组高血压大鼠-一组未经野生模拟人参治疗的大鼠; 另一组用100 mg野生模拟人参提取物/ kg体重治疗;另一组在8周内接受了200 mg野生模拟人参提取物/ kg体重的治疗。两个野生模拟人参治疗组在野生模拟人参治疗的第4周和第6周显示收缩压显着降低(p <0.05)。但是,野外模拟人参治疗对食物摄入,血清电解质,重量克分子渗透压浓度,心重,心率,和主动脉的横截面以及酶的活性。结果表明,韩国野生模拟人参可有效降低高血压患者的收缩压,而不会引起不良健康影响。
更新日期:2019-11-01
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