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Blood lactate, pH, base excess and pCO2 as prognostic indicators in caesarean-born kids from goats with pregnancy toxaemia.
Irish Veterinary Journal ( IF 2.7 ) Pub Date : 2019-10-14 , DOI: 10.1186/s13620-019-0149-1
I M Andrade 1 , P B A Simões 1 , L P Lamas 1 , N Carolino 1, 2 , M S Lima 1
Affiliation  

The objective of this study was to identify the prognostic value for survival of blood parameters in the immediate post-caesarean surgery period in kids born from pregnancy toxaemia (PT) goats. This study involved 10 PT goats, in which a caesarean surgery was performed. Twenty-five kids were born after caesarean surgery of which 16 survived. A blood sample was collected from the jugular vein of the 10 goats and from the kids immediately after caesarean surgery (within 15 min). There were differences between the kids that survived and the kids that did not survive concerning the blood levels of pH (7.22 vs 7.00), base excess (- 9 vs - 18 mmol/L), pCO2 (46 vs 62 mmHg) and L-lactate (5.6 vs 16 mmol/L). Maternal ketoacidosis due to PT has a negative impact on the survival rate of the offspring. This appears to be associated to a metabolic acidosis of the offspring. However, the only blood parameter in which there was a strong association between the maternal and newborn kids was blood urea nitrogen (r = 0.97).

中文翻译:

血液中乳酸,pH,碱过量和pCO2可作为妊娠毒血症山羊剖腹产婴儿的预后指标。

这项研究的目的是确定在剖腹产后立即进行的妊娠毒血症(PT)山羊出生的孩子中血液参数的生存的预后价值。这项研究涉及10 PT山羊,其中进行了剖腹产手术。剖腹产手术后出生了25个孩子,其中16个幸存。在剖腹产手术后(15分钟内)立即从10只山羊的颈静脉和孩子那里采集血样。存活的孩子与未存活的孩子之间的区别在于血液的pH值(7.22 vs 7.00),碱过量(-9 vs-18 mmol / L),pCO2(46 vs 62 mmHg)和L-乳酸盐(5.6对16 mmol / L)。PT引起的母体酮症酸中毒对后代的存活率具有负面影响。这似乎与后代的代谢性酸中毒有关。但是,唯一与母婴有密切联系的血液参数是血液尿素氮(r = 0.97)。
更新日期:2020-04-23
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