当前位置: X-MOL 学术WIREs Mech. Dis. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The amphipod crustacean Parhyale hawaiensis: An emerging comparative model of arthropod development, evolution, and regeneration.
WIREs Mechanisms of Disease ( IF 4.6 ) Pub Date : 2019-06-11 , DOI: 10.1002/wdev.355
Dennis A Sun 1 , Nipam H Patel 2
Affiliation  

Recent advances in genetic manipulation and genome sequencing have paved the way for a new generation of research organisms. The amphipod crustacean Parhyale hawaiensis is one such system. Parhyale are easy to rear and offer large broods of embryos amenable to injection, dissection, and live imaging. Foundational work has described Parhyale embryonic development, while advancements in genetic manipulation using CRISPR‐Cas9 and other techniques, combined with genome and transcriptome sequencing, have enabled its use in studies of arthropod development, evolution, and regeneration. This study introduces Parhyale development and life history, a catalog of techniques and resources for Parhyale research, and two case studies illustrating its power as a comparative research system.

中文翻译:

两栖类甲壳动物Parhyale hawaiensis:节肢动物发育,进化和再生的新兴比较模型。

基因操作和基因组测序的最新进展为新一代研究生物铺平了道路。两栖类甲壳类的夏威夷Parhyale就是这样一种系统。杂草很容易饲养,并提供适合注射,解剖和实时成像的大量胚。基础工作描述了Parhyale胚胎的发育,同时使用CRISPR‐Cas9和其他技术进行基因操作的进展与基因组和转录组测序相结合,使其能够用于节肢动物的发育,进化和再生研究中。这项研究介绍了Parhyale的发展和生活史,Parhyale的技术和资源目录 研究和两个案例研究说明了其作为比较研究系统的力量。
更新日期:2019-06-11
down
wechat
bug