Noble metal nanoparticles (NPs) and their hybrids have demonstrated a strong potential to mimic the catalytic activity of natural enzymes and diminish oxidative stress. There is a large space to explore the intrinsic catalytic activity of Rh NPs with respect to reactive oxygen species (ROS) scavenging. We found that Rh NPs can quench H2O2, •OH, O2•-, 1O2 and inhibit lipid peroxidation under physiological conditions. In vitro cell experiments proved that Rh NPs have great biocompatibility and protect cells from oxidative damage caused by H2O2. This study can provide important insights that could inform future biological applications.

中文翻译：

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铑纳米粒子对活性氧清除的内在催化活性：降低细胞毒性的含义。

贵金属纳米颗粒（NPs）及其杂化物已显示出强大的潜力，可以模仿天然酶的催化活性并减少氧化应激。有很大的空间来探索Rh NPs对活性氧（ROS）清除的固有催化活性。我们发现Rh NPs可以在生理条件下淬灭H2O2，•OH，O2•-，1O2并抑制脂质过氧化。体外细胞实验证明，Rh NP具有很好的生物相容性，可以保护细胞免受H2O2引起的氧化损伤。这项研究可以提供重要的见识，可以为将来的生物学应用提供参考。