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Exploring the immunogenome with bioinformatics.
Seminars in Immunology ( IF 7.4 ) Pub Date : 2003-08-01 , DOI: 10.1016/s1044-5323(03)00049-6
Bernard de Bono 1 , John Trowsdale
Affiliation  

A better description of the immune system can be afforded if the latest developments in bioinformatics are applied to integrate sequence with structure and function. Clear guidelines for the upgrade of the bioinformatic capability of the immunogenetics laboratory are discussed in the light of more powerful methods to detect homology, combined approaches to predict the three dimensional properties of a protein and a robust strategy to represent the biological role of a gene.

中文翻译:

用生物信息学探索免疫基因组。

如果将生物信息学的最新发展应用于整合序列与结构和功能,则可以更好地描述免疫系统。根据更强大的同源性检测方法、预测蛋白质三维特性的组合方法以及代表基因生物学作用的稳健策略,讨论了免疫遗传学实验室生物信息学能力升级的明确指南。
更新日期:2019-11-01
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