Fatty acids have diverse roles in all cells. They are important as a source of energy, as structural components of cell membranes, as signalling molecules and as precursors for the synthesis of eicosanoids. Recent research has suggested that the organization of fatty acids into distinct cellular pools has a particularly important role in cells of the immune system and that forms of lipid trafficking exist, which are as yet poorly understood. This Review examines the nature and regulation of cellular lipid pools in the immune system, their delivery of fatty acids or fatty acid derivatives to specific locations and their potential role in health and disease.

中文翻译：

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脂肪酸是免疫细胞调节的守门员。

脂肪酸在所有细胞中都有不同的作用。它们作为能源，细胞膜的结构成分，信号分子和类花生酸合成的前体非常重要。最近的研究表明，将脂肪酸组织成不同的细胞池在免疫系统的细胞中起着特别重要的作用，并且存在脂质运输的形式，目前人们对此知之甚少。这篇综述研究了免疫系统中细胞脂质池的性质和调节，脂肪酸或脂肪酸衍生物向特定部位的传递以及它们在健康和疾病中的潜在作用。