Pesticides are widely used throughout the world in agriculture to protect crops, and in public health to control diseases transmitted by animal vectors or intermediate hosts. After the prohibition of organochlorines such as DDT internal exposure of the general population to the organochlorines has been reduced markedly. Herein, current internal exposure of children and adolescents in an urban area in Germany to PCP, lindane, and DDT/E is reported. One hundred and thirty children and adolescents took part in this voluntary investigation. All of them stated they had never used pesticides in their homes or for medical reasons. Blood plasma was analysed for pentachlorophenol (PCP), lindane (gamma-HCH), and dichloro(diphenyl)ethylene (DDE), a biostable metabolite of dichloro(diphenyl)trichloroethane (DDT), using gas chromatography/electron capture detection according to well established methods approved by the Deutsche Forschungsgemeinschaft. Median (and 95th percentiles) in the age groups < 6, 6- < 12, and 12- < 18 years of age were (microgram/l): DDE: 0.75 (4.45), 0.95 (5.04), 0.89 (8.77); DDT: < 0.1 (0.22), < 0.1 (0.25), < 0.1 (0.30); PCP: 2.48 (17.32), 2.69 (5.85), 2.08 (8.04); lindane: < 0.1 (0.12, < 0.1 (0.08), < 0.1 (0.09). High levels of internal exposure to DDT in two girls were probably obtained during a holiday stay in India; high PCP-levels in two other girls were caused by a leather jacket impregnated with PCP, and a holiday abroad, respectively. Current background levels of internal exposure to organochlorine insecticides in children and adolescents in Germany are quantified. Exposure to these substances in the general population is thought to occur mainly via residues in food, which are low in general, today. In special cases, however, individual exposures may be dominated by other sources, i.e. impregnated leather clothes.

中文翻译：

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德国目前在儿童和青少年中对农药的内部暴露：血浆中五氯苯酚（PCP），林丹（γ-六氯环己烷）和二氯（二苯基）乙烯（DDE）的水平，二氯（二苯基）三氯乙烷（DDT）的生物稳定代谢产物。

农药在世界范围内广泛用于农业中，以保护农作物，并在公共卫生中，用于控制由动物媒介或中间宿主传播的疾病。在禁止使用诸如DDT之类的有机氯之后，普通人群内部暴露于有机氯的现象已大大减少。本文报道了德国城市地区儿童和青少年当前内部接触五氯苯酚，林丹和DDT / E的情况。一百三十名儿童和青少年参加了这项自愿调查。他们所有人都表示，他们从未在家中或出于医疗原因使用过农药。分析血浆中的五氯苯酚（PCP），林丹（gamma-HCH）和二氯（二苯基）乙烯（DDE），即二氯（二苯基）三氯乙烷（DDT）的生物稳定代谢物，根据Deutsche Forschungsgemeinschaft认可的完善方法，使用气相色谱/电子捕获检测。<6，6- <12和12- <18岁年龄组的中位数（和95％百分位数）为（微克/升）：DDE：0.75（4.45），0.95（5.04），0.89（8.77）; 滴滴涕：<0.1（0.22），<0.1（0.25），<0.1（0.30）; PCP：2.48（17.32），2.69（5.85），2.08（8.04）；林丹：<0.1（0.12，<0.1（0.08），<0.1（0.09）。印度度假期间可能有两个女孩体内高水平的DDT暴露；另外两个女孩的PCP高水平是由于分别是浸有五氯苯酚的皮夹克和出国度假，对德国儿童和青少年内部有机氯杀虫剂内部暴露的当前背景水平进行了量化。据认为，一般人群中这些物质的暴露主要是通过食物中的残留物发生的，而今天这些食物中的残留物普遍较低。但是，在特殊情况下，个人暴露可能会受到其他来源的影响，例如浸渍皮革衣服。