In the last 30 years many research showed that high serum cholesterol level is a great risk for the atherosclerosis. In recent years, it has become clear that the immune system has a major role in atherosclerosis development and progression, and has binding capacity to cholesterol as well. It has been demonstrated in animal experiments, that anti-cholesterol antibodies (ACHA) can prevent cholesterol diet induced atherosclerosis. Our group is looking for the answer, whether ACHA have the same function in animals and in humans, or not. In this review we summarize our studies in human sera. We measured serum ACHA levels in different groups of patients with atherosclerotic diseases in patients with viral infections and in healthy population. In the summary we write about the possible functions of ACHA in the human immune system.

中文翻译：

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人血清中的抗胆固醇抗体。

在过去的30年中，许多研究表明，高血清胆固醇水平是动脉粥样硬化的巨大风险。近年来，已经清楚的是，免疫系统在动脉粥样硬化的发生和发展中具有重要作用，并且还具有与胆固醇的结合能力。在动物实验中已经证明，抗胆固醇抗体（ACHA）可以预防胆固醇饮食诱发的动脉粥样硬化。我们的小组正在寻找答案，无论ACHA在动物和人类中是否具有相同的功能。在这篇综述中，我们总结了我们在人类血清中的研究。我们测量了不同组的动脉粥样硬化疾病患者，病毒感染患者和健康人群的血清ACHA水平。在总结中，我们介绍了ACHA在人类免疫系统中的可能功能。