A chitosan Schiff base with an aromatic aldehyde was synthesized and characterized by FTIR and NMR spectroscopies. Furthermore, the degree of substitution was calculated based on the ratios of the area of the proton of the imine (Aimine ) and the area of the peak of the proton of the pyranose ring (AH-2 ). The antimicrobial activities were determined against bacterial and fungal strains, as well as multiple drug-resistant (MDR) bacteria. The chitosan Schiff base was also tagged with medicinal plants, for example, Curcuma longa, Peganum harmala, Lepidium sativam, and cruciferous vegetables, and the biological activities determined against pathogenic bacterial and fungal strains. The chitosan Schiff base showed maximum zone of inhibition of 22 mm against Staphylococcus aureus with a minimum zone of inhibition of 15 mm against Bacillus cereus. The chitosan Schiff base was fused with C longa, isothiocyanates and a combined mixture of P harmala and L sativam that has shown activities against Escherichia coli with a zone of inhibition of 28, 24, and 30 mm, respectively. The Schiff base of chitosan fused with medicinal plants also showed significant inhibitory activities against MDR bacteria.

中文翻译：

---

药用植物标记壳聚糖席夫碱的生物活性评价

合成了具有芳香醛的壳聚糖席夫碱，并通过 FTIR 和 NMR 光谱对其进行了表征。此外，取代度基于亚胺(Aimine )的质子面积与吡喃糖环(AH-2 )的质子峰面积之比计算。确定了对细菌和真菌菌株以及多重耐药 (MDR) 细菌的抗菌活性。壳聚糖席夫碱还标记了药用植物，例如姜黄、胡桃、禾本科和十字花科蔬菜，并确定了对病原细菌和真菌菌株的生物活性。壳聚糖希夫碱对金黄色葡萄球菌的最大抑制区为 22 mm，对蜡样芽孢杆菌的最小抑制区为 15 mm。壳聚糖席夫碱与 C longa、异硫氰酸酯和 Pharmala 和 L sativam 的组合混合物融合，后者已显示出对大肠杆菌的活性，抑制区分别为 28、24 和 30 毫米。与药用植物融合的壳聚糖希夫碱也对 MDR 细菌显示出显着的抑制活性。