We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and haplotypic frequencies. The most frequent haplotypes for the Baja California region include nine Native American and five European haplotypes. Admixture estimates revealed that the main genetic components are European (50.45 ± 1.84% by ML; 42.03% of European haplotypes) and Native American (43.72 ± 2.36% by ML; 40.24% of Native American haplotypes), while the African genetic component was less apparent (5.83 ± 0.98% by ML; 9.36% of African haplotypes).

我们研究了HLA I类（HLA-A，-B）和II类（HLA-DRB1，-DQB1）基于PCR-SSP的等位基因，来自生活在墨西卡利（N = 100），拉巴斯（N = 75），蒂华纳（N = 25）和农村社区（N）的下加利福尼亚州北下加利福尼亚州和南下加利福尼亚州的250名墨西哥人= 50），以获得有关等位基因和单倍型频率的信息。下加利福尼亚州地区最常见的单体型包括九种美洲原住民和五种欧洲单体型。混合物估计显示，主要遗传成分是欧洲（按ML分类为50.45±1.84％；欧洲单倍型的42.03％）和美国原住民（按ML分类的为43.72±2.36％；美国原住民单倍型的40.24％），而非洲遗传成分较少明显（按ML值分别为5.83±0.98％;非洲单倍型的9.36％）