Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a previous study by Mandairon et al., which suggested that the olfactory preferences of mice and humans are similar. A probabilistic examination revealed that underpowered studies can result in spurious significant correlations, which can account for the differences between both studies. Future analyses aimed at dissecting the olfactory preferences across species need to test large numbers of odorants to stress-test the model proposed here and identify robust associations.

中文翻译：

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蝇，小鼠和人类的嗅觉偏好的种间差异。

为了揭示嗅觉偏好之间的种间差异，我们对果蝇，小鼠和人类的气味价进行了比较研究。我们的分析提出了一个模型，其中果蝇和小鼠具有相似的嗅觉偏好，但没有一个物种与人类共享气味偏好。该模型与Mandairon等人先前的研究相反，后者表明小鼠和人类的嗅觉偏好相似。概率检查表明，能力不足的研究可能导致虚假的显着相关，这可以解释这两项研究之间的差异。旨在剖析物种嗅觉偏好的未来分析需要测试大量的气味剂，以对此处提出的模型进行压力测试并确定稳固的关联。