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Monoamine oxidase and cigarette smoking.
NeuroToxicology ( IF 3.4 ) Pub Date : 2003-02-05 , DOI: 10.1016/s0161-813x(02)00109-2
Joanna S Fowler 1 , Jean Logan , Gene-Jack Wang , Nora D Volkow
Affiliation  

Current cigarette smokers have reduced monoamine oxidase (MAO) and there is evidence that this is a pharmacological effect of tobacco smoke exposure rather than a biological characteristic of smokers. This article summarizes human and animal studies documenting the inhibitory effects of tobacco smoke on MAO and discusses MAO inhibition in the context of smoking epidemiology, MAO inhibitor compounds in tobacco, reinvestigations of low platelet MAO in psychiatric disorders and smoking cessation.

中文翻译:

单胺氧化酶和吸烟。

当前的吸烟者已经减少了单胺氧化酶(MAO),并且有证据表明,这是接触烟草烟雾的药理作用,而不是吸烟者的生物学特征。本文总结了人类和动物研究,这些研究记录了烟草烟雾对MAO的抑制作用,并讨论了吸烟流行病学,烟草中的MAO抑制剂化合物,精神病性疾病中低血小板MAO的重新研究和戒烟等方面的MAO抑制作用。
更新日期:2019-11-01
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