Lyme disease is currently the most common vector-borne illness in the United States. The disease is multisystemic, and chronic disease, in particular, may be associated with neuropsychological deficits. However, to date, only a few empirical studies exist, which examine the neuropsychological sequelae associated with chronic Lyme disease. A review of the literature shows that the deficits observed in adults with chronic Lyme disease are generally consistent with the deficits that can be seen in processes with primarily frontal systems involvement. These observations are generally consistent with neuroradiologic findings. The clinical presentation in chronic Lyme disease and the nature of the neuropsychological deficits are discussed, as are several central issues in understanding neuropsychological functioning in chronic Lyme disease, such as the impact of chronic illness, response to treatment, and the relationship between neuropsychological performance and depression, fatigue, and neurological indicators of disease.

中文翻译：

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慢性莱姆病的神经心理功能。

莱姆病目前是美国最常见的媒介传播疾病。该疾病是多系统的，特别是慢性疾病可能与神经心理缺陷有关。然而，迄今为止，只有少数实证研究存在，这些研究检查了与慢性莱姆病相关的神经心理后遗症。对文献的回顾表明，在患有慢性莱姆病的成年人中观察到的缺陷通常与在主要涉及额叶系统的过程中可以看到的缺陷一致。这些观察结果通常与神经放射学发现一致。讨论了慢性莱姆病的临床表现和神经心理缺陷的性质，以及了解慢性莱姆病的神经心理功能的几个核心问题，