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Caveolae: from cell biology to animal physiology.
Pharmacological Reviews ( IF 19.3 ) Pub Date : 2002-09-12 , DOI: 10.1124/pr.54.3.431
Babak Razani 1 , Scott E Woodman , Michael P Lisanti
Affiliation  

Among the membrane compartments of a cell, vesicles known as "caveolae" have long defied functional characterization. However, since the identification of a family of proteins termed "caveolins", that form and reside in caveolae, a better understanding has emerged. It is now clear that caveolae do not merely play a singular role in the cell, but are pleiotropic in nature-serving to modulate many cellular functions. The purpose of this review is to explicate what is known about caveolins/caveolae and highlight growing areas of caveolar research.

中文翻译:

小窝:从细胞生物学到动物生理学。

在细胞的膜区室中,被称为“小泡”的囊泡长期以来一直缺乏功能特征。然而,由于鉴定了形成并存在于小窝中的称为“小窝蛋白”的蛋白质家族,因此出现了更好的理解。现在清楚的是,海绵小窝不仅在细胞中发挥独特作用,而且在性质上具有多效性,可调节许多细胞功能。这篇综述的目的是阐明已知的小窝蛋白/小窝并强调小窝研究的增长领域。
更新日期:2019-11-01
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