The purpose of this study was to analyze the relation of total body weight to longevity and mortality. The MEDLINE database was searched for data that allow analysis of the relationship between absolute body weight and longevity or mortality. Additional data were used involving US veterans and baseball players. Trend lines of age at death versus body weight are presented. Findings show absolute body size is negatively related to longevity and life expectancy and positively to mortality. Trend lines show an average age at death versus weight slope of -0.4 years/kg. We also found that gender differences in longevity may be due to differences in body size. Animal research is consistent with the findings presented. Biological mechanisms are also presented to explain why increased body mass may reduce longevity. Life expectancy has increased dramatically through improved public health measures and medical care and reduced malnutrition. However, overnourishment and increased body size have promoted an epidemic of chronic disease and reduced our potential longevity. In addition, both excess lean body mass and fat mass may promote chronic disease.

中文翻译：

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长寿，死亡率和体重。

这项研究的目的是分析总体重与寿命和死亡率的关系。在MEDLINE数据库中搜索数据，以分析绝对体重与寿命或死亡率之间的关系。使用了涉及美国退伍军人和棒球运动员的其他数据。给出了死亡年龄与体重的趋势线。研究结果表明，绝对体型与寿命和寿命负相关，与死亡率成正相关。趋势线显示平均死亡年龄与体重的斜率-0.4年/公斤。我们还发现，长寿中的性别差异可能是由于体型差异造成的。动物研究与提出的发现一致。还提出了生物学机制来解释为什么体重增加可能会降低寿命。通过改善公共卫生措施和医疗保健以及减少营养不良，预期寿命已大大增加。但是，营养过剩和体型增大已经促进了慢性病的流行，并降低了我们的潜在寿命。另外，多余的瘦体重和脂肪都会促进慢性疾病。