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New advances in the chemistry of methoxylated lipids.
Progress in Lipid Research ( IF 13.6 ) Pub Date : 2002-08-10 , DOI: 10.1016/s0163-7827(02)00005-x
N M Carballeira 1
Affiliation  

Methoxylated lipids have been reviewed emphasizing the alkylglycerol ethers and fatty acids bearing the methoxy group in the alkyl chain. The literature on methoxylated lipids and their derivatives has been divided into four main groups, namely 2-methoxylated alkyl glycerols, omega-methoxylated fatty acids, mid-chain methoxylated fatty acids, and alpha-methoxylated fatty acids. The natural occurrence, biological activity, and synthesis of this interesting group of lipids are discussed. Most of these compounds have been isolated from either bacterial or marine sources, but others are mainly of synthetic origin. Among the interesting biological activities displayed by these compounds the most important are antibacterial, antifungal, antitumor, and antiviral.

中文翻译:

甲氧基化脂质化学的新进展。

甲氧基化脂质已被综述,强调烷基甘油醚和在烷基链上带有甲氧基的脂肪酸。关于甲氧基化脂质及其衍生物的文献已分为四个主要组,即2-甲氧基化烷基甘油,ω-甲氧基化脂肪酸,中链甲氧基化脂肪酸和α-甲氧基化脂肪酸。讨论了这种有趣的脂质的天然存在,生物活性和合成。这些化合物大多数已从细菌或海洋来源中分离出来,但其他化合物主要是合成来源。这些化合物显示出有趣的生物学活性,其中最重要的是抗菌,抗真菌,抗肿瘤和抗病毒。
更新日期:2019-11-01
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