The present preliminary study attempts to establish associations between milk production traits and genetic polymorphisms at the GH gene in the Algarvia goat. The DNA of 108 goats of the indigenous Portuguese Algarvia breed was evaluated. Single-strand conformation polymorphisms (SSCP) were identified at the five exons of the goat growth hormone (gGH) gene. Two conformational patterns were found in each of exons 1 and 2, four in exon 3, six in exon 4 and five in exon 5. An association between these SSCP patterns with milk, fat and protein production, and fat and protein content was examined. Patterns F/F of exon 4 and A/A of exon 5 were positively associated with milk production (P<0.05). The results demonstrated that the gGH gene could be exploited as a candidate gene for marker-assisted selection in goat breeds.

中文翻译：

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阿尔加维亚山羊生长激素基因五个外显子的多态性：可能与牛奶性状有关

目前的初步研究试图建立阿尔加维亚山羊产奶性状和 GH 基因遗传多态性之间的关联。对 108 只葡萄牙本土阿尔加维亚山羊品种的 DNA 进行了评估。在山羊生长激素 (gGH) 基因的五个外显子处鉴定出单链构象多态性 (SSCP)。在外显子 1 和 2 中发现了两种构象模式，外显子 3 中有 4 个，外显子 4 中有 6 个，外显子 5 中有 5 个。研究了这些 SSCP 模式与牛奶、脂肪和蛋白质产量以及脂肪和蛋白质含量之间的关联。外显子4的F/F和外显子5的A/A模式与产奶量呈正相关（P<0.05）。结果表明，gGH 基因可用作山羊品种标记辅助选择的候选基因。