Skin exposure to chemicals in the workplace environment is a major concern, the hands being the major exposure sites. Employers purchase gloves that have permeation data generated from permeation “standards” of the American Society for Testing and Materials International (ASTM International), European Committee for Standardization (EN), and the International Organization for Standardization (ISO) that test pieces of glove material and allow a user-defined temperature. The relevant standards based on continuous contact are ASTM F739, ASTM D6978, EN 374, EN 16523, and ISO 6529. The aim was to analyze the current state of the scientific literature on glove permeation in the 21^st century up to December 2018. The introduction sets out the background, objectives and rationale of the review and its methodology followed by presentation of basic glove chemical resistance terms and Fick’s first law of diffusion, the details of the major permeation standards, their comparison, their critique, their research gaps; the scientific literature on whole glove permeation, and final conclusions. The major recommendation was to harmonize all the permeation standards and perform them at realistic work conditions, especially temperature. The whole glove system would be most useful for testing the thinnest gloves.

工作场所环境中皮肤接触化学品是一个主要问题，手是主要接触部位。雇主购买的手套具有根据美国测试与材料国际协会 (ASTM International)、欧洲标准化委员会 (EN) 和国际标准化组织 (ISO) 的渗透“标准”生成的渗透数据，用于测试手套材料并允许用户定义温度。基于持续接触的相关标准有 ASTM F739、ASTM D6978、EN 374、EN 16523 和 ISO 6529。目的是分析截至 2018 年 12 月的²¹世纪手套渗透科学文献的现状。引言阐述了审查的背景、目标和基本原理及其方法，随后介绍了基本的手套耐化学性术语和菲克第一扩散定律、主要渗透标准的详细信息、它们的比较、批评和研究差距；关于整个手套渗透的科学文献和最终结论。主要建议是协调所有渗透标准并在实际工作条件（尤其是温度）下执行这些标准。整个手套系统对于测试最薄的手套最有用。