PURPOSE OF REVIEW To integrate evidence on the role of circadian rhythm in male reproduction. Several studies report on various aspects of the association between the circadian system and male reproductive function in animals and humans both in physiological condition as well as in the case of subfertility. RECENT FINDINGS Epidemiological data demonstrate diurnal and seasonal changes as well as the effect of sleep/wake cycles on the quality of semen. Rare and common genetic variation in circadian clock genes in humans and animal models support the role of circadian rhythms in male fertility in humans. SUMMARY Current data support the modest effect of the circadian clock on male reproductive potential; however, the evidence available is still fragmented and inconclusive. Additional well designed and sufficiently powered studies are needed to delineate the role of the circadian clock both in cause and potential interventional and preventive approaches in male subfertility.

中文翻译：

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昼夜节律在男性生殖中的作用。

综述的目的整合昼夜节律在男性生殖中的作用的证据。几项研究报告了生理条件下以及在不育情况下动物和人类中昼夜节律系统与男性生殖功能之间的关联的各个方面。最近的发现流行病学数据表明，昼夜和季节变化以及睡眠/唤醒周期对精液质量的影响。人类和动物模型中昼夜节律基因的稀有和常见遗传变异支持昼夜节律在人类雄性生殖中的作用。小结当前的数据支持了生物钟对男性生殖潜能的适度影响。然而，现有的证据仍然是零散的和不确定的。