The Human Genome Project (HGP) is one of the most important international achievements in life sciences, to which Japanese scientists made remarkable contributions. In the early 1980s, Akiyoshi Wada pioneered the first project for the automation of DNA sequencing technology. Ken-ichi Matsubara exhibited exceptional leadership to launch the comprehensive human genome program in Japan. Hideki Kambara made a major contribution by developing a key device for high-speed DNA sequencers, which enabled scientists to construct human genome draft sequences. The RIKEN team led by Yoshiyuki Sakaki (the author) played remarkable roles in the draft sequencing and completion of chromosomes 21, 18, and 11. Additionally, the Keio University team led by Nobuyoshi Shimizu made noteworthy contributions to the completion of chromosomes 22, 21, and 8. In April 2003, the Japanese team joined the international consortium in declaring the completion of the human genome sequence. Consistent with the HGP mandate, Japan has successfully developed a wide range of ambitious genomic sciences.

中文翻译：

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日本人类基因组计划的历史。


人类基因组计划（HGP）是生命科学领域最重要的国际成就之一，日本科学家对此做出了卓越贡献。 20 世纪 80 年代初，Akiyoshi Wada 开创了第一个 DNA 测序技术自动化项目。松原健一 (Ken-ichi Matsubara) 在日本启动综合人类基因组计划方面展现了卓越的领导才能。 Hideki Kambara 做出了重大贡献，开发了高速 DNA 测序仪的关键设备，使科学家能够构建人类基因组草图序列。由Yoshiyuki Sakaki（作者）领导的RIKEN团队在21、18和11号染色体的草稿测序和完成中发挥了卓越的作用。此外，Nobuyoshi Shimizu领导的庆应义塾大学团队在22、21号染色体的完成中也做出了值得注意的贡献、 8、2003年4月，日本团队加入国际联盟，宣布完成人类基因组测序。根据人类基因组计划的任务，日本已成功开发了一系列雄心勃勃的基因组科学。