Calcium phosphate cement (CPC) has been studied extensively due to its bioactivity and biodegradability. CPC is typically made by a combination of multiple calcium phosphates that form a paste that sets and hardens in the body after being combined with either water or an aqueous solution. It is highly moldable and easily manipulated, and CPCs possess osteoconductive properties. Due to these characteristics, CPCs offer great promise in bone grafting applications. CPC combined with drugs has a great potential as drug delivery system and has been studied extensively. In this review we have focused on Bisphosphonate-CPC drug delivery system. In addition, we introduce and discuss the potential of studying other bisphosphonates.

中文翻译：

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双膦酸酯-磷酸钙水泥复合材料及其性能。

磷酸钙水泥（CPC）由于其生物活性和可生物降解性而被广泛研究。CPC通常是由多种磷酸钙组合而成，形成的糊状物在与水或水溶液混合后会在体内凝固并硬化。它具有很高的可塑性和易于操作性，并且CPC具有骨传导特性。由于这些特性，CPC在植骨应用中提供了广阔的前景。CPC结合药物作为药物输送系统具有巨大的潜力，并且已被广泛研究。在这篇综述中，我们重点介绍了双膦酸盐-CPC药物递送系统。此外，我们介绍并讨论了研究其他双膦酸酯的潜力。