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Mechanical Properties of the Cytoskeleton and Cells.
Cold Spring Harbor Perspectives in Biology ( IF 6.9 ) Pub Date : 2017-11-03 , DOI: 10.1101/cshperspect.a022038
Adrian F Pegoraro 1 , Paul Janmey 2 , David A Weitz 1
Affiliation  

SUMMARYThe cytoskeleton is the major mechanical structure of the cell; it is a complex, dynamic biopolymer network comprising microtubules, actin, and intermediate filaments. Both the individual filaments and the entire network are not simple elastic solids but are instead highly nonlinear structures. Appreciating the mechanics of biopolymer networks is key to understanding the mechanics of cells. Here, we review the mechanical properties of cytoskeletal polymers and discuss the implications for the behavior of cells.

中文翻译:

细胞骨架和细胞的机械性能。

概述细胞骨架是细胞的主要机械结构。它是一个复杂的动态生物聚合物网络,包括微管,肌动蛋白和中间丝。单个细丝和整个网络都不是简单的弹性固体,而是高度非线性的结构。理解生物聚合物网络的机制是理解细胞机制的关键。在这里,我们审查细胞骨架聚合物的机械性能,并讨论对细胞行为的影响。
更新日期:2019-11-01
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