Wnt signalling pathway is widely studied in many processes of biological development, like embryogenesis, tissue homeostasis and wound repair. It is universally known that Wnt signalling pathway plays an important role in tooth development. Here, we summarized the function of Wnt signalling pathway during tooth initiation, crown morphogenesis, root formation, and discussed the therapeutic potential of Wnt modulators.

中文翻译：

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Wnt信号通路在牙齿发育和潜在临床应用中的进展。

Wnt信号通路在许多生物学发展过程中得到了广泛研究，例如胚胎发生，组织稳态和伤口修复。众所周知，Wnt信号通路在牙齿发育中起着重要作用。在这里，我们总结了Wnt信号通路在牙齿萌发，冠形态发生，根形成过程中的功能，并讨论了Wnt调节剂的治疗潜力。