Malignant peritoneal mesothelioma is a very rare tumor originating from the peritoneal serous mesothelium. Meningeal metastasis of malignant peritoneal is even more rare. Here, we reported a case of a 60-year-old female patient with a history of exposure to asbestos for 10 years who presented with massive peritoneal effusion followed by disorder of consciousness and symptoms of cranial nerve injury. The patient was diagnosed as peritoneal mesothelioma with meningeal metastasis through neurological symptoms, cytological finding of cerebrospinal fluid combined with cranial magnetic resonance imaging (MRI). The patient received systemic chemotherapy and total craniospinal irradiation. The follow up visits showed that the survival time of patient after diagnosis of meningeal metastasis from peritoneal mesothelioma was 5 months. To our knowledge, this is the first case of menigeal metastasis of peritoneal mesothelioma. We hope this particular case may be helpful in providing some experience to the treatment of peritoneal mesothelioma with meningeal metastasis.

中文翻译：

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恶性腹膜间皮瘤的脑膜转移：一例报告并文献复习。

恶性腹膜间皮瘤是一种非常罕见的起源于腹膜浆膜间皮瘤的肿瘤。恶性腹膜的脑膜转移更为罕见。在这里，我们报道了一例60岁的女性患者，该患者有10年的接触石棉史，表现为腹膜大量积液，继而出现意识障碍和颅神经损伤症状。通过神经系统症状，脑脊液细胞学检查结合颅脑磁共振成像（MRI）诊断为腹膜间皮瘤伴脑膜转移。患者接受了全身化学疗法和全颅脊髓照射。随访表明，腹膜间皮瘤确诊为脑膜转移后患者的生存时间为5个月。据我们所知，这是腹膜间皮瘤半月板转移的第一例。我们希望这种特殊情况可能有助于为腹膜间皮瘤伴脑膜转移的治疗提供一些经验。