Electrospraying (ES) is a robust and versatile technique for the fabrication of micro- and nanoparticulate materials of various compositions, morphologies, shapes, textures and sizes. The physics of ES provides a great degree of flexibility towards the materials design of choice with desired physicochemical and biological properties. Not surprising, this technology has become an important tool for the production of micro- and nanostructured materials, especially in the pharmaceutical and biomedical arena. In this review, a basic introduction to the fundamentals of ES along with a brief description of the experimental parameters that can be manipulated to obtain micro- and nanostructured materials of desired composition, size, and configuration are outlined. A greater focus of this review is to bring to light the broad range of electrosprayed materials and their applications in drug delivery, biomedical imaging, implant coating, tissue engineering, and sensing. Taken together, this review will provide an appreciation of this unique technology, which can be used to fabricate micro- and nanostructured materials with tremendous applications in the pharmaceutical and biomedical fields.

中文翻译：

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电喷雾是制药和生物医学应用的一项使能技术：综述

电喷雾 (ES) 是一种稳健且通用的技术，用于制造各种成分、形态、形状、纹理和尺寸的微米和纳米颗粒材料。ES 的物理学为具有所需物理化学和生物特性的材料设计选择提供了极大的灵活性。毫不奇怪，这项技术已成为生产微米和纳米结构材料的重要工具，特别是在制药和生物医学领域。在这篇综述中，概述了 ES 的基本原理，并简要描述了可以操纵以获得所需成分、尺寸和配置的微米和纳米结构材料的实验参数。本次综述的一个更大的重点是揭示广泛的电喷涂材料及其在药物输送、生物医学成像、植入物涂层、组织工程和传感方面的应用。总而言之，这篇综述将提供对这种独特技术的评价，该技术可用于制造微米和纳米结构材料，在制药和生物医学领域具有巨大的应用。