BACKGROUND In the first 5 years after their stroke, about a quarter of patients will suffer from a recurrent stroke. Digital health interventions facilitating interactions between a caregiver and a patient from a distance are a promising approach to improve patient adherence to lifestyle changes proposed by secondary prevention guidelines. Many of these interventions are not implemented in daily practice, even though efficacy has been shown. One of the reasons can be the lack of clear economic incentives for implementation. We propose to map all health economic evidence regarding digital health interventions for secondary stroke prevention. SUMMARY We performed a systematic search according to PRISMA-P guidelines and searched on PubMed, Web of Science, Cochrane, and National Institute for Health Research Economic Evaluation Database. Only digital health interventions for secondary prevention in stroke patients were included and all study designs and health economic outcomes were accepted. We combined the terms "Stroke OR Cardiovascular," "Secondary prevention," "Digital health interventions," and "Cost" in one search string using the AND operator. The search performed on April 20, 2017 yielded 163 records of which 26 duplicates were removed. After abstract screening, 20 articles were retained for full-text analysis, of which none reported any health economic evidence that could be included for analysis or discussion. Key Messages: There is a lack of evidence on health economic outcomes on digital health interventions for secondary stroke prevention. Future research in this area should take health economics into consideration when designing a trial and there is a clear need for health economic evidence and models.

中文翻译：

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中风患者二级预防数字健康干预措施的卫生经济学评估：系统评价。

背景技术在中风后的前5年内，大约四分之一的患者会复发中风。数字健康干预措施促进护理人员与患者之间的远距离互动，是提高患者对二级预防指南提出的生活方式改变依从性的一种有前景的方法。尽管已显示出有效性，但其中许多干预措施并未在日常实践中实施。原因之一可能是缺乏明确的实施经济激励措施。我们建议绘制有关二级中风预防的数字健康干预措施的所有健康经济证据。摘要 我们根据 PRISMA-P 指南进行了系统检索，并在 PubMed、Web of Science、Cochrane 和国立卫生研究院经济评估数据库上进行了检索。仅纳入针对中风患者二级预防的数字健康干预措施，并且所有研究设计和健康经济结果均被接受。我们使用 AND 运算符将术语“中风或心血管”、“二级预防”、“数字健康干预”和“成本”合并在一个搜索字符串中。2017 年 4 月 20 日进行的检索产生了 163 条记录，其中删除了 26 条重复记录。经过摘要筛选，保留了20篇文章进行全文分析，其中没有一篇报道了可以纳入分析或讨论的健康经济学证据。关键信息：缺乏关于中风二级预防的数字健康干预措施的健康经济成果的证据。该领域的未来研究在设计试验时应考虑健康经济学，并且显然需要健康经济学证据和模型。